C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/44 (2006.01) A61K 31/4035 (2006.01) A61K 31/4155 (2006.01) A61P 39/06 (2006.01) C07D 403/04 (2006.01)
Patent
CA 2738799
The invention relates to antioxidant substituted isoindoline nitroxide compounds and their use in methods of treating or preventing diseases or disorders related to oxidative stress, methods of reducing oxidative stress and methods of protecting a subject from oxidative stress upon exposure to ionising radiation. Pharmaceutical compositions comprising the antioxidant compounds are also described.
La présente invention concerne des composés de nitroxyde d'isoindoline substitués par des antioxydants et leur utilisation dans le cadre de procédés de traitement ou de prévention de maladies ou d'affections associées au stress oxydatif, des procédés de réduction du stress oxydatif et des procédés permettant de protéger un sujet contre le stress oxydatif faisant suite à son exposition à des rayonnements ionisants. L'invention concerne également des compositions pharmaceutiques comprenant lesdits composés antioxydants.
Bottle Steven
Fairfull-Smith Kathryn
Schill Farina
Queensland University Of Technology
Ridout & Maybee Llp
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