Antiparasitic 6,8a-seco deoxyavermectin derivatives

Details Antiparasitic 6,8a-seco deoxyavermectin derivatives Antiparasitic 6,8a-seco deoxyavermectin derivatives

C - Chemistry, Metallurgy

12

N

C12N 1/20 (2006.01) A01N 43/90 (2006.01) A61K 31/35 (2006.01) C07D 493/20 (2006.01) C07H 19/01 (2006.01) C12P 17/08 (2006.01) C12P 17/18 (2006.01) C12P 19/62 (2006.01) A61K 31/71 (1995.01)

Patent

CA 2147758

An antiparasitic compound of formula (I), (II) or (III) wherein R is selected from a variety of organic groups, the broken line optional double bond, R1 is H, OH, -O-alkyl or optionally substituted oximino, and R2 and R3 are H, OH, H, OMe, oxo, optionally substituted oximino or optionally substituted amino.

Composé antiparasitaire de formule (I), (II) ou (III), où R est choisi parmi divers groupes organiques, la ligne en pointillé représente une double liaison facultative, R1 est H, OH, -O-alkyle ou un oximino avec substitution facultative, R2 et R3 représentent H, OH, H, OMe, un oxo, un oximino avec substitution facultative ou un amino avec substitution facultative.

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