Antiparasitic agent for fish and method of controlling...

A - Human Necessities – 61 – K

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Details

A61K 45/06 (2006.01) A61K 31/42 (2006.01) A61K 31/433 (2006.01) A61K 31/505 (2006.01) A61K 31/519 (2006.01) A61K 31/635 (2006.01) A61P 33/02 (2006.01) A61P 43/00 (2006.01) C07D 239/69 (2006.01) C07D 261/16 (2006.01) C07D 285/12 (2006.01) C07D 475/04 (2006.01) C07D 475/08 (2006.01)

Patent

CA 2759155

Disclosed is a method for controlling fish parasites, which comprises continuously administering a folic acid synthesis inhibitor and/or a folic acid activation inhibitor to a fish at a dose of 1 to 50 mg/kg fish body weight per day for one to two weeks. Preferably, a combination of a folic acid synthesis inhibitor and a folic acid activation inhibitor is used. As the folic acid synthesis inhibitor, a sulfa drug is preferred. As the folic acid activation inhibitor, a dihydrofolate reductase inhibitor, a folic acid antagonist, or the like can be used. The parasite control agent can control fish parasites through oral administration. The parasite control agent is particularly effective on ciliate fish parasites.

L'invention porte sur un procédé de lutte contre des parasites des poissons qui comporte l'administration continue quotidienne d'un inhibiteur de synthèse d'acide folique et/ou d'un inhibiteur d'activation d'acide folique à un poisson à une dose de 1 à 50 mg/kg de poids corporel du poisson pendant une à deux semaines. De préférence, une combinaison d'un inhibiteur de synthèse d'acide folique et d'un inhibiteur d'activation d'acide folique est utilisée. En tant qu'inhibiteur de synthèse d'acide folique, un médicament sulfamide est préféré. En tant qu'inhibiteur d'activation d'acide folique, un inhibiteur de dihydrofolate réductase, un antagoniste d'acide folique, ou autre, peut être utilisé. L'agent de lutte contre les parasites peut lutter contre des parasites des poissons par une administration orale. L'agent de lutte contre des parasites est particulièrement efficace contre des parasites des poissons ciliés.

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