Antiparasitic agents

Details Antiparasitic agents Antiparasitic agents

C - Chemistry, Metallurgy

12

P

195/101, 167/185

C12P 17/18 (2006.01) A01N 43/90 (2006.01) A61K 31/70 (2006.01) C07H 19/01 (2006.01) C12N 1/20 (2006.01) C12P 19/44 (2006.01) C12P 19/62 (2006.01)

Patent

CA 1339965

N787-182 antibiotic compounds and derivatives of the formula Image wherein the substituents R, R1, R2 and R3 are as follows: Compound R R1 R2 R3 N787-182 - 1 CH3 OH OH H N787-182 - 2 H OH OH OCOCH(CH3)2 N787-182 - 3 CH3 OH OH OCOCH(CH3)2 N787-182 - 4 H OCOCH(CH3)2 OH H N787-182 - 5 CH3 OCOCH(CH3)2 OH H N787-182 - 6 H OCOCH(CH3)2 OH OCOCH(CH3)2 N787-182 - 7 CH3 OCOCH(CH3)2 OH OCOCH(CH3)2 N787-182 - 9 H OCOCH(CH3)2 H H N787-182 - 10 CH3 OCOCH(CH3)CH2CH3 OH OCOCH(CH3)2 N787-182 - 11 CH3 H OH OCOCH(CH3)2 N787-182 - 12 CH3 OCOCH(CH3)2 H H Compound - 13 H OH OH H are antiparasitic agents active against insect pests, acari, free-living nematodes and endo- and ectoparasites. The N787-182 antibiotics are prepared by fermentation using the microorganism Streptomyces hygroscopicus ATCC 53718 on January 27, 1988.

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