Antiparasitic agents

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 19/01 (2006.01) A01N 43/90 (2006.01) A61K 31/70 (2006.01) C07H 17/08 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2165806

Novel antiparasitic compounds of formula (I), wherein the broken line represents an optional bond, R1 and R4 being absent when this bond is present, R1, R3, R4 are independently H, OH, halo, mercapto, oxo, oximino, or an organic radical, R2 and R7 are organic radicals, R6 is H or an organic radical and R12 is OH, halo, C1-C8 alkoxy, C1-C9 alkanoyloxy or oximino optionally O-substituted by a C1-C8 alkyl, alkenyl, alkynyl, aryl, trialkylsilyl, aralkyl or C1-C9 alkanoyl group.

Nouveaux composés antiparasitaires de formule (I), dans laquelle la ligne interrompue représente une liaison optionnelle, R1 et R4 étant absents lorsque cette liaison est présente, R1, R3 et R4 sont indépendamment H, OH, halo, mercapto, oxo, oximino ou un radical organique, R2 et R7 sont des radicaux organiques, R6 est H ou un radical organique et R12 est OH, halo, alcoxy C1-C8, alcanoyloxy C1-C9 ou oximino optionnellement substitué sur O par un groupe alkyle, alcényle, alcynyle, aryle, trialkylsilyle, aralkyle C1-C8 ou un groupe alcanoyle C1-C9.

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