Antipicornaviral compouds, compositions containing them, and...

Details Antipicornaviral compouds, compositions containing them, and... Antipicornaviral compouds, compositions containing them, and...

C - Chemistry, Metallurgy

07

C

C07C 271/22 (2006.01) A61K 31/325 (2006.01) A61K 31/44 (2006.01) C07C 271/34 (2006.01) C07C 333/04 (2006.01) C07D 207/26 (2006.01) C07D 209/08 (2006.01) C07D 213/30 (2006.01) C07D 261/08 (2006.01) C07D 261/18 (2006.01) C07D 339/06 (2006.01) C07D 339/08 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2289541

Picornaviral 3C protease inhibitors of formula (I) obtainable by chemical synthesis, inhibit or block the biological activity of the picornaviral 3C protease. These compounds of formula (I), wherein M is O or S, as well as pharmaceutical compositions that contain these compounds, are suitable for treating patients or hosts infected with one or more picornaviruses.

Cette invention se rapporte à des inhibiteurs de protéase 3C picornavirale de formule (I), que l'on produit par synthèse chimique, et qui inhibent ou bloquent l'activité biologique de la protéase 3C picornavirale. Ces composés représentés par la formule (I), dans laquelle M est O ou S, ainsi que les compositions pharmaceutiques qui contiennent ces composés, sont adaptés au traitement de patients ou d'hôtes infestés par un ou plusieurs picornavirus.

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