C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/88 (2006.01) A61K 31/422 (2006.01) A61K 31/427 (2006.01) A61K 31/433 (2006.01) C07D 277/40 (2006.01) C07D 277/46 (2006.01) C07D 307/68 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/10 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2720176
Inhibitors of the oncogenic tyrosine kinase ALK and of the Bcr-Ab1 mutant T315I Bcr-Ab1, such as a compound of formula (I) wherein Q, T, W, K, J, Y, X, Z are independently selected from C, N, S, O, provided that the corresponding rings are (hetero)aromatic; n=0 or 1; q=1 or 2; pharmaceutical compositions containing the same and their use for the treatment of hyperproliferative diseases.
L'invention concerne des inhibiteurs de la tyrosine kinase oncogène ALK et du mutant T315I Bcr-Abl de Bcr-Abl, des compositions pharmaceutiques les contenant ainsi que leur utilisation pour le traitement des maladies hyperprolifératives.
Ahmed Shaheen
Gambacorti Passerini Carlo
Goekjian Peter G.
Gueyrard David
Gunby Rosalind Helen
Kirby Eades Gale Baker
Universita'degli Studi Di Milano-Bicocca
Universite Claude Bernard - Lyon 1
Universite de Geneve
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