Antiproliferative compounds based on 5-membered heterocycles

Details Antiproliferative compounds based on 5-membered heterocycles Antiproliferative compounds based on 5-membered heterocycles

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/41 (2006.01) A61K 31/4427 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2692379

The present invention encompasses com-pounds of general formula (1) wherein the groups R2 to R4 L, Q and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or ab-normal cell proliferation, and their use for preparing a phar-maceutical composition with the above-mentioned proper-ties.

L'invention concerne des composés chimiques de formule générale (1), dans laquelle les groupes R2 à R4, L, Q et n sont défini tel que dans la revendication 1. Ces composés conviennent au traitement de maladies caractérisées par une prolifération excessive ou anormale de cellules et sont utilisés dans la préparation d'une composition pharmaceutique possédant les propriétés susmentionnées.

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