A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2609069
Conjugates between hyaluronic acid and N-derivatives of glutamic acid, are further esterified on the residual primary hydroxyl groups of the hyaluronic acid with an aminoacid, a peptide, an aliphatic acid, an arilaliphatic acid and/or arylic acid a significant and unexpected increase in their antiproliferative activity and decrease in their toxicity is observed.
La présente invention porte sur des conjugués estérifiés de l'acide hyaluronique ayant une activité antiproliférative.
Bergamin Massimo
Flaibani Antonella
Khan Riaz Ahmed
Murano Erminio
Norbedo Stefano
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Eurand Pharmaceuticals Limited
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