Antiproliferative naphthyridines

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/435 (2006.01)

Patent

CA 2161436

The present invention relates to the deriva- tives of the formula Image and their addition salts, and to their use in thera- peutics, especially as drugs having antiproliferative properties and affording an effective treatment for diseases such as cancer, psoriasis, atherosclerosis, restenosis phenomena or any other pathological condi- tion due to cell proliferation.

La présente invention concerne les dérivés de formule (I), ainsi que leurs sels d'addition et leur utilisation en thérapeutique notamment comme médicaments à propriétés antiprolifératives et permettant de traiter efficacement les maladies comme le cancer, le psoriasis, l'athérosclérose, les phénomènes de resténose ou tout autre pathologie due à une prolifération cellulaire.

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