C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/02 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/435 (2006.01) A61K 31/485 (2006.01) A61K 31/535 (2006.01) A61K 31/5377 (2006.01) A61K 31/54 (2006.01) C07D 489/00 (2006.01) C07D 489/08 (2006.01) C07D 519/00 (2006.01)
Patent
CA 2244256
This invention provides an antipruritic comprising an opiate .kappa. receptor agonist as an effective component, a new morphinan quaternary ammonium salt derivative and a new morphinan-N-oxide derivative which are useful in treating pruritus complicated with some diseases.
L'invention porte sur un agent antiprurigineux comportant comme principe actif un agoniste du récepteur opioïde kappa et utilisable pour le traitement du prurit de différentes maladies accompagnées de prurit. L'invention concerne également de nouveaux dérivés d'un sel d'ammonium quaternaire de morphinane et de n-oxymorphinane.
Endoh Takashi
Kamei Junzo
Kawamura Kuniaki
Nagase Hiroshi
Tanaka Toshiaki
Smart & Biggar
Toray Industries Inc.
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