Antiretroviral hydrazine derivatives

Details Antiretroviral hydrazine derivatives Antiretroviral hydrazine derivatives

C - Chemistry, Metallurgy

07

C

C07C 271/20 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) C07C 243/34 (2006.01) C07C 271/22 (2006.01) C07C 275/16 (2006.01) C07D 207/16 (2006.01) C07D 207/34 (2006.01) C07D 213/55 (2006.01) C07D 213/79 (2006.01) C07D 215/48 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 233/90 (2006.01) C07D 295/13 (2006.01) C07D 295/155 (2006.01) C07D 307/68 (2006.01) C07D 309/04 (2006.01) C07D 333/20 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2112047

Abstract Antiretroviral Hydrazine Derivatives Compounds of formula Image (I), wherein R1 and R9 are each independently of the other hydrogen; acyl; unsubstituted or substituted alkyl; sulfo; or sulfonyl substituted by unsubstituted or substituted alkyl, aryl or by hetero- cyclyl, with the proviso that not more than one of the radicals R1 and R9 is hydrogen; and R2 and R8 are each independently of the other hydrogen or unsubstituted or substituted alkyl; R3 and R4 are each independently of the other hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; R5 is acyloxy; R6 is hydrogen; and R7 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; and salts of the mentioned compounds where salt-forming groups are present, are described; those compounds exhibit antiretroviral activity.

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