C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7125 (2006.01) A61P 31/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2392685
The invention relates to compositions comprising oligomers antisense to bacterial 16S or 23S rRNA and capable of selectively modulating the biological activity thereof, and methods for their use. More particularly, the invention relates to antisense oligomers directed to 16S or 23S rRNA found in one or more particular bacteria, or generally conserved among bacteria in general, and to pharmaceutical compositions and methods of treatment comprising the same.
La présente invention concerne des compositions comprenant des oligomères d'antisens aux bactéries d'ARNr 16S ou 23S et capables de moduler de manière sélective l'activité biologique de celles-ci, et leur procédés d'utilisation. Plus particulièrement, l'invention concerne des oligomères d'antisens dirigés contre les ARNr 16S ou 23S qui se trouvent dans une ou plusieurs bactéries spécifiques, ou qui se conservent parmi les bactéries en général, et des compositions pharmaceutiques les comprenant et des procédés de traitement les utilisant.
Avi Biopharma Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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