Antisense base sequences

Details Antisense base sequences Antisense base sequences

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A01H 5/00 (2006.01) C12N 15/29 (2006.01) C12N 15/82 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2254785

A novel technique for enhancing, in the techniques for inhibiting the synthesis of proteins, the inhibitory effects with the use of antisense base sequences. Specifically, antisense base sequences containing two or more sequences of desired structural genes or parts of the same consecutively linked in the antisense direction; expression vectors having the above antisense base sequences; products of transformation by the above expression vectors; and a method for inhibiting the expression of proteins by using the above antisense base sequences.

Nouvelle méthode permettant, dans les techniques destinées à inhiber la synthèse des protéines, d'améliorer les effets inhibiteurs au moyen de séquences de bases antisens. De manière spécifique, séquences de bases antisens contenant au moins deux séquences des gènes de structure désirés ou de parties desdits gènes, liées de manière consécutive dans la direction antisens; vecteurs d'expression comportant lesdites séquences de bases antisens; produits de la transformation par lesdits vecteurs d'expression; et méthode permettant d'inhiber l'expression des protéines au moyen desdites séquences de base antisens.

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