Antisense compositions and methods of making and using same

Details Antisense compositions and methods of making and using same Antisense compositions and methods of making and using same

C - Chemistry, Metallurgy

12

N

C12N 15/113 (2010.01) A61K 31/7088 (2006.01)

Patent

CA 2743329

The present invention provides pharmaceutical formulations for oral administration of antisense oligonucleotides, such as antisense oligonucleotides against SMAD7. The pharmaceutical formulations can be used to treat Crohn's disease, ulcerative colitis and chronic inflammatory bowel disease.

La présente invention concerne des formulations pharmaceutiques pour administration orale doligonucléotides antisens, tels que des oligonucléotides antisens contre SMAD7. Les formulations pharmaceutiques peuvent être utilisées pour traiter la maladie de Crohn, la recto-colite hémorragique et une affection abdominale inflammatoire.

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