C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61P 25/00 (2006.01) A61P 27/02 (2006.01)
Patent
CA 2547780
Methods and compositions for modulating the activities of connexins are provided, including, for example, for use in post-surgical, trauma, or tissue engineering applications. These compounds and methods can be used therapeutically, for example, to reduce the severity of adverse effects associated diseases and disorders where localized disruption in direct cell- cell communication is desirable.
L'invention concerne des méthodes et des compositions pour moduler l'activité de connexines, y compris, par exemple, dans des applications post-chirurgicales, lors de traumas ou en ingénierie de tissus. Ces composés et ces méthodes peuvent être utilisés, par exemple, pour réduire la sévérité des troubles et maladies associés à des effets indésirables, lorsqu'il est souhaitable d'intervenir au niveau des communications directes entre cellules.
Green Colin R.
Laux Wilda
Coda Therapeutics (nz) Ltd
Smart & Biggar
LandOfFree
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