Antisense compounds to cd14

Details Antisense compounds to cd14 Antisense compounds to cd14

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2253877

Oligonucleotides and derivatives thereof containing sequences which are hybridizable whith, or complementary to a part of a gene encoding human CD14; and medicinal compositions containing as the active ingredient these oligonucleotides or derivatives thereof. These medicinal compositions are useful in treating diseases such as systemic inflammatory response syndrome.

L'invention concerne des oligonucléotides et dérivés de ceux-ci, contenant des séquences qui peuvent s'hybrider avec, ou qui sont complémentaires d'une partie d'un gène codant le CD14 humain. Elle porte aussi sur des compositions médicinales dont le principe actif est constitué par ces oligonucléotides ou des dérivés de ceux-ci. Ces compositions médicinales sont utiles dans le traitement de maladies telles que le syndrome de réaction inflammatoire systémique.

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