A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/713 (2006.01)
Patent
CA 2731214
A room temperature stable and minimal aggregate liquid formulation comprises an oligonucleotide comprising Seq ID No. 1: or comprising a variant oligonucleotide in which no more than 3 non- sequential bases are different from Seq. ID NO. 1 and an aqueous carrier comprising a aggregation-preventing compound selected from the group consisting of mono and disaccha-rides and/or sugar alcohols.
La présente invention concerne une formulation liquide dagrégat stable à température ambiante et minimal comprenant un oligonucléotide comprenant Seq ID No. 1: ou comprenant un oligonucléotide variant dans lequel pas plus de 3 bases non séquentielles sont différentes de Seq. ID NO. 1 et un véhicule aqueux comprenant un composé de prévention dagrégation choisi dans le groupe constitué de mono et disaccharides et/ou de polyols.
Hayes Thomas K.
Krilla Nicole D.
Nixon Lori
Gowling Lafleur Henderson Llp
Oncogenex Technologies Inc.
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