Antisense inhibition of angiogenin expression

Details Antisense inhibition of angiogenin expression Antisense inhibition of angiogenin expression

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2293591

Disclosed are oligonucleotide compounds that inhibit the expression of angiogenin when administered to a mammal. Also disclosed are methods and pharmaceutical compositions for inhibiting the expression of angiogenin useful in therapy or diagnosis.

La présente invention concerne des composés oligonucléotides qui, administrés à un mammifère, inhibent l'expression de l'angiogénine. L'invention concerne également des procédés et des compositions pharmaceutiques permettant d'inhiber l'expression de l'angiogénine et convenant particulièrement à des applications thérapeutiques ou de diagnostic.

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