C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2248213
The present invention pertains to a method for treating a patient with a disease in which the levels of interleukin-10 need to be down-regulated which comprises administering to the patient a therapeutically effective amount of an antisense oligodeoxynucleotide specific for interleukin-10 mRNA. The present invention also pertains to an antisense oligodeoxynucleotide specific for interleukin-10 mRNA having the formula 5'-TGGGTCTTGGTTCTCAGCTTGGGGCAT.
Cette invention se rapporte à un procédé servant à traiter un patient qui souffre d'une maladie dans laquelle les niveaux d'interleukine-10 doivent être régulés à la baisse, ce procédé consistant à administrer à ce patient une quantité, efficace sur le plan thérapeutique, d'un oligodésoxynucléotide anti-sens spécifique de l'ARNm de l'interleukin-10. Cette invention se rapporte également à un oligodésoxynucléotide anti-sens spécifique de l'ARNm de l'interleukine-10 ayant la formule 5'-TGGGTCTTGGTTCTCAGCTTGGGGCAT.
Smart & Biggar
University Of Medicine & Dentistry Of New Jersey
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