Antisense modulation of cellular inhibitor of apoptosis-2...

Details Antisense modulation of cellular inhibitor of apoptosis-2... Antisense modulation of cellular inhibitor of apoptosis-2...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2353108

Antisense compounds, compositions and methods are provided for modulating the expression of Cellular Inhibitor of Apoptosis-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Cellular Inhibitor of Apoptosis-2. Methods of using these compounds for modulation of Cellular Inhibitor of Apoptosis-2 expression and for treatment of diseases associated with expression of Cellular Inhibitor of Apoptosis-2 are provided.

L'invention concerne des composés antisens, des compositions et des procédés permettant de moduler l'expression d'un inhibiteur cellulaire de l'apoptose-2. Les compositions renferment des composés antisens, spécialement des oligonucléotides antisens, ciblés sur des acides nucléiques codant l'inhibiteur cellulaire de l'apoptose-2. Les procédés consistent à utiliser ces composés pour moduler l'expression de l'inhibiteur cellulaire d'apoptose-2 et pour traiter les maladies liées à l'expression de l'inhibiteur cellulaire de l'apoptose-2.

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