Antisense modulation of glycogen synthase kinase 3 beta...

Details Antisense modulation of glycogen synthase kinase 3 beta... Antisense modulation of glycogen synthase kinase 3 beta...

A - Human Necessities

61

K

A61K 31/7088 (2006.01) A61K 31/7115 (2006.01) A61K 31/712 (2006.01) A61K 31/7125 (2006.01) C07H 21/00 (2006.01) C12N 5/06 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2396697

Antisense compounds, compositions and methods are provided for modulating the expression of glycogen synthase kinase 3 beta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding glycogen synthase kinase 3 beta. Methods of using these compounds for modulation of glycogen synthase kinase 3 beta expression and for treatment of diseases associated with expression of glycogen synthase kinase 3 beta are provided.

L'invention concerne des composés antisens, des compositions et des procédés servant à moduler l'expression de glycogène synthase kinase 3 bêta. Les compositions contiennent des composés antisens, en particulier des oligonucléotides antisens, ciblés sur des acides nucléiques codant pour la glycogène synthase kinase 3 bêta. L'invention concerne des procédés d'utilisation de ces composés pour moduler l'expression de glycogène synthase kinase 3 bêta, et pour traiter des maladies associées à l'expression de glycogène synthase kinase 3 bêta.

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