Antisense modulation of integrin-linked kinase expression

Details Antisense modulation of integrin-linked kinase expression Antisense modulation of integrin-linked kinase expression

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07H 21/02 (2006.01) C12N 9/12 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2389036

Antisense compounds, compositions and methods are provided for modulating the expression of Integrin-linked kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Integrin-linked kinase. Methods of using these compounds for modulation of Integrin-linked kinase expression and for treatment of diseases associated with expression of Integrin-linked kinase are provided.

L'invention concerne des composés antisens, des compositions et des procédés servant à moduler l'expression de kinase liée aux intégrines. Les compositions comprennent des composés antisens, en particulier des oligonucléotides antisens, ciblés sur des acides nucléiques codant pour la kinase liée aux intégrines. L'invention concerne des procédés d'utilisation de ces composés pour moduler l'expression de kinase liée aux intégrines et pour traiter des maladies associées à l'expression de kinase liée aux intégrines.

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