Antisense modulation of phospholipid scramblase i expresion

Details Antisense modulation of phospholipid scramblase i expresion Antisense modulation of phospholipid scramblase i expresion

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2443641

Antisense compounds, compositions and methods are provided for modulating the expression of Phospholipid scramblase I. The compositions comprise antisense compounds, particularly antisense olignonucleotides, targeted to nucleic acids encoding Phospholipid scramblase I expression and for treatment of diseases associated with expression of Phospholipid scramblase I are provided.

L'invention porte sur des composés antisens, sur des compositions et sur des procédés visant à moduler l'expression de la scramblase I phospholipidique. Les compositions comprennent des composés antisens, notamment des olignonucléotides antisens, ciblés sur les acides nucléiques codant l'expression de la scramblase I phospholipidique. L'invention porte également sur des procédés d'utilisation de ces composés dans la modulation de l'expression de la scramblase I phospholipidique et dans le traitement de maladies associées à l'expression de la scramblase I phospholipidique.

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