C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) A61K 48/00 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2377437
Antisense compounds, compositions and methods are provided for modulating the expression of Ship-2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Ship-2. Methods of using these compounds for modulation of Ship-2 expression and for treatment of diseases associated with expression of Ship-2 are provided.
L'invention concerne des composés antisens, des compositions et des procédés servant à moduler l'expression de Ship-2. Les compositions comprennent des composés antisens, notamment des oligonucléotides antisens, qui ciblent des acides nucléiques codant pour Ship-2. L'invention concerne aussi des procédés d'utilisation de ces composés pour moduler l'expression de Ship-2 et pour traiter des maladies associées à l'expression de Ship-2.
Bennett C. Frank
Cowsert Lex M.
Borden Ladner Gervais Llp
Isis Pharmaceuticals Inc.
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