C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/02 (2006.01) A61K 48/00 (2006.01) C07C 21/04 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2343102
Antisense compounds, compositions and methods are provided for modulating the expression of Survivin. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding Survivin. Methods of using these compounds for modulation of Survivin expression and for treatment of diseases associated with expression of Survivin are provided.
La présente invention concerne des composés anti-sens, des compositions et procédés correspondants permettant de moduler l'expression de la survivine. Ces compositions comprennent des composés anti-sens, notamment des oligonucléotides anti-sens, ciblés sur des acides nucléiques codant la survivine. L'invention concerne également des modes d'utilisation de ces composés pour la modulation de l'expression de la survivine, et pour le traitement d'affections associées à l'expression de la survivine.
Ackermann Elizabeth J.
Bennett C. Frank
Cowsert Lex M.
Swayze Eric E.
Borden Ladner Gervais Llp
Isis Pharmaceuticals Inc.
Isis Pharmaceuticals Inc.
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