C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61P 31/04 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2392094
The present invention provides antisense oligonucleotides which modulate the expression of the groEL or groES genes in microorganisms. This invention is also related to methods of using such oligonucleotides in inhibiting the growth of microorganisms. These antisense oligonucleotides are particularly useful in treating pathological conditions in mammals which are mediated by the growth of microorganisms.
L'invention concerne des oligonucléotides antisens qui modulent l'expression des gènes groEL ou groES dans des micro-organismes. L'invention a également trait à des procédés d'utilisation de ces oligonucléotides pour inhiber la croissance de micro-organismes. Ces oligonucléotides antisens sont particulièrement utiles pour traiter chez des mammifères des états pathologiques qui dépendent de la croissance de micro-organismes.
Dugourd Dominique
Wright Jim A.
Young Aiping H.
Genesense Technologies Inc.
Mbm Intellectual Property Law Llp
LandOfFree
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