A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7105 (2006.01) A61P 1/00 (2006.01) C12N 15/11 (2006.01)
Patent
CA 2648980
The present invention relates to novel uses of antisense oligonucleotides targeted to the coding region of acetylcholinesterase (AChE) for treating inflammatory disorders other than inflammatory disorders of the central nervous system or the peripheral nervous system innervating voluntary muscles. More particularly, the present invention relates to uses of antisense oligodexoynucleotides targeted to AChE mRNA for treating inflammatory disease of the gastrointestinal tract including inflammatory bowel disease.
La présente invention concerne de nouvelles utilisations d'oligonucléotides antisens dirigés contre la région codant pour l'acétylcholinestérase (AChE) dans le traitement de troubles inflammatoires autres que les troubles inflammatoires du système nerveux central ou du système nerveux périphérique innervant les muscles volontaires. Plus particulièrement, la présente invention concerne des utilisations d'oligodésoxynucléotides antisens dirigés contre l'ARNm de l'AChE dans le traitement d'une maladie inflammatoire du tractus gastro-intestinal, comprenant la maladie intestinale inflammatoire.
Carmon Lior
Hazum Eli
Borden Ladner Gervais Llp
Ester Neurosciences Ltd.
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