C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2461477
This invention relates to the inhibition and down-regulation of survivin expression. The invention provides methods and antisense oligonucleotides for inhibiting or down-regulating survivin expression in cells and promoting apoptosis and cell necrosis.
L'invention concerne l'inhibition et la diminution du taux d'expression de la survivine. L'invention concerne également des méthodes et des oligonucléotides antisens permettant d'inhiber ou de diminuer le taux d'expression de la survivine dans les cellules et de stimuler l'apoptose et la nécrose cellulaire.
Agrawal Sudhir
Kandimalla Ekambar R.
Mani Sridhar
Shafit-Zagardo Bridget
Shankar Sai Latha
Albert Einstein College Of Medicine Of Yeshiva University
Hybridon Inc.
Smart & Biggar
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