Antisense oligonucleotides and therapeutic use thereof in...

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 21/00 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2165821

The present invention is directed to oligonucleotides comprising nucleotide sequences sufficiently complementary to conserved regions of human immunodeficiency virus genetic material such that when bound to said region, the oligonucleotides effectively reduce expression of HIV genetic material.

L'invention porte sur des oligonucléotides comprenant des séquences nucléotidiques suffisamment complémentaires de régions conservées du matériel génétique du VIH pour qu'une fois liés auxdites régions les oligonucléotides réduisent efficacement l'expression du matériel génétique du VIH.

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