Antisense oligonucleotides comprising universal and/or...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12P 19/34 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2365984

Antisense oligonucleotides containing one or more degenerate and/or universal bases, and one or more modified backbone linkages, and use of these oligonucleotides for cleaving target RNA molecules.

L'invention concerne des oligonucléotides anti-sens contenant une ou plusieurs bases dégénérées et/ou universelles, ainsi qu'une ou plusieurs liaisons de squelette modifiées, et l'utilisation de ces oligonucléotides pour cliver des molécules d'ARN cibles.

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