Antisense oligonucleotides directed against ribonucleotide...

Details Antisense oligonucleotides directed against ribonucleotide... Antisense oligonucleotides directed against ribonucleotide...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01)

Patent

CA 2535650

The present invention provides antisense oligonucleotides directed to a mammalian ribonucleotide reductase R2 gene and combinations of the antisense oligonucleotides with one or more chemotherapeutic agents for use in the treatment of cancer.

L'invention porte: sur des oligonucléotides antisens se dirigeant vers le gène de ribonucléotide réductase R2 de mammifère, et sur leur combinaison, avec un ou plusieurs agents de chimiothérapie, utilisée pour le traitement du cancer.

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