A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 31/7088 (2006.01) A61K 31/7125 (2006.01) A61K 38/19 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2553211
Combination products comprising an antisense oligonucleotide against the gene encoding a mammalian ribonucleotide reductase R2 protein and one or more immunotherapeutic agents, such as cytokines, non-cytokine adjuvants, monoclonal antibodies and cancer vaccines. The combinations can further comprise one or more chemotherapeutic agents. Methods of treating cancer in a mammal using the combinations are also provided.
La présente invention concerne des produits de combinaison comprenant un oligonucléotide antisens dirigé contre le gène codant pour la protéine de la ribonucléotide réductase R2 chez un mammifère et un ou plusieurs agents immunothérapeutiques, tels que des cytokines, des adjuvants non-cytokines, des anticorps monoclonaux et des vaccins contre le cancer. Les combinaisons décrites dans cette invention peuvent également comprendre un ou plusieurs agents chimiothérapeutiques. Cette invention concerne également des méthodes permettant de traiter un cancer chez un mammifère au moyen des combinaisons susmentionnées.
Lee Yoon S.
Wright Jim A.
Young Aiping H.
Genesense Technologies Inc.
Lorus Therapeutics Inc.
Mbm Intellectual Property Law Llp
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