Antisense oligonucleotides (odn) against smad7 and uses...

Details Antisense oligonucleotides (odn) against smad7 and uses... Antisense oligonucleotides (odn) against smad7 and uses...

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2520541

The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn~s disease and ulcerative colitis.

Cette invention concerne des séquences oligonucléotidiques antisens (ODN) dirigées contre Smad7 modifiées de manière adéquate et concerne également leurs utilisations dans le domaine médical en tant qu'agents biologiques thérapeutiques, en particulier dans le traitement de maladies intestinales inflammatoires chroniques, telles que la maladie de Crohn et la colite ulcéreuse.

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