Antisense oligonucleotides to c-myb oncogene and uses thereof

Details Antisense oligonucleotides to c-myb oncogene and uses thereof Antisense oligonucleotides to c-myb oncogene and uses thereof

A - Human Necessities

61

K

167/202, 195/1.1

A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2004364

ANTISENSE OLIGONUCLEOTIDES TO C-MYB PROTO-ONCOGENE AND USES THEREOF Abstract of the Disclosure Oligonucleotides are provided having a nucleotide sequence complementary to at least a portion of the mRNA transcript of the human c-myb gene. These "antisense" oligonucleotides are hybridizable to the c-myb mRNA transcript. Such oligonucleotides are useful in treating hematologic neoplasms and in inducing immunosuppression. They are particularly useful as bone marrow purging agents. 6056-72 (CIP)2 CN /tep

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