Antisense permeation enhancers

Details Antisense permeation enhancers Antisense permeation enhancers

C - Chemistry, Metallurgy

07

H

C07H 21/04 (2006.01) A61K 9/00 (2006.01) A61K 9/127 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 31/20 (2006.01) A61K 31/7088 (2006.01) A61K 47/12 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2447444

A pharmaceutical composition comprising an antisense oligonucleotide and a permeation enhancer that comprises a multi-carbon backbone having a functional group and also one or more side chains which have one or more carbon atoms and, optionally, one or more functional groups.

La présente invention concerne une composition pharmaceutique comprenant un oligonucléotide antisens et un renforçateur de perméation qui comprend une ossature à plusieurs carbones disposant d'un groupe fonctionnel et aussi d'une ou plusieurs chaînes latérales qui ont un ou plusieurs atomes de carbone, et facultativement, un ou plusieurs groupes fonctionnels.

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