Antisense strategy for viral insecticides

A - Human Necessities – 01 – N

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A01N 63/00 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2177509

A novel type of insect control agent and methods for controlling insect pests are described. The agent consists of a vector, such as a baculovirus of the polyhedral inclusion body type, containing in an antisense orientation cDNA sequence which has been derived from the complete sense sequence of a gene which is essential for the growth and development of the host from which the sequence is derived. In order for the insect control agent to exert its effect the insect pests which are to be controlled must be susceptible to the vector. Specifically described are the sequences from Choristoneura fumiferana and the human c-myc gene as well the methods of production and use of these agents.

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