Antispasmodic agents

Details Antispasmodic agents Antispasmodic agents

C - Chemistry, Metallurgy

07

D

167/209, 260/291

C07D 417/06 (2006.01) A61K 31/55 (2006.01) C07D 207/09 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2017535

The invention provides compounds of the formula:- (see above formula) wherein k is 1, 2 or 3; m is 1, 2 or 3; n is 1, 2 or 3; P is 0, 1 or 2; X is O; S or a direct link, with the proviso that when X is O or S; n is 2 or 3; R1 is H or C1-C4 alkyl; and R2 is an optionally substituted phenyl or heteroaryl group; and pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of motility disorders, particularly those of the gut such as irritable bowel syndrome.

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