C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 221/16 (2006.01) A61K 51/04 (2006.01) A61P 15/16 (2006.01) A61P 15/18 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) G01N 33/567 (2006.01) A01N 43/42 (2006.01) A01P 3/00 (2006.01)
Patent
CA 2649713
Hexahydroindenopyridine compounds are disclosed which act as contraceptive agents by disrupting spermatogenesis, acting as spermicides or sperm motility inhibitors and/or act as antifungals; antlspermatogenic, sperm motility inhibitors, spermicidal or antifungal compositions containing the compounds; and methods for disrupting spermatogenesis, inhibiting sperm motility, killing motile sperm or treating fungi using the compounds and compositions. Also disclosed are radioactive compounds which may be used to study the binding of antifertility compounds to specific sites in the body and the use of such compounds for that purpose.
La présente invention a pour objet des hexahydroindénopyridines qui agissent en tant qu'agents contraceptifs par perturbation de la spermatogenèse, en tant que spermicides ou inhibiteurs de motilité du sperme et/ou en tant qu'antifongiques; des compositions antispermatogènes, inhibitrices de motilité du sperme, spermicides ou antifongiques contenant les composés; et des méthodes de perturbation de la spermatogenèse, d'inhibition de la motilité du sperme, d'élimination du sperme motile ou de traitement de champignons utilisant les composés et les compositions. La présente invention a également pour objet des composés radioactifs qui peuvent être employés dans l'étude de la liaison de composés anti-fertilité à des sites spécifiques de l'organisme et l'emploi de tels composés dans ce but.
Cook Clarence Edgar
Navarro Hernan Andres
Tallent Clyde Ray
Thomas Brian Frazier
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Research Triangle Institute
LandOfFree
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