Antithrombogenic composition and methods of making same

Details Antithrombogenic composition and methods of making same Antithrombogenic composition and methods of making same

A - Human Necessities

61

L

167/323

A61L 33/00 (2006.01)

Patent

CA 2038596

ANTITHROMBOGENIC COMPOSITION AND METHODS OF MAKING SAME ABSTRACT OF THE DISCLOSURE An antithrombogenic composition comprising an anticoagulant bound to processed collagen. A method of preparing an antithrombogenic material useful in medical applications is provided wherein said the protein of processed collagen to which anticoagulant is bound is fixed by a cross-linking agent. A method of preparing an antithrombogenic material useful as a coating for conventional medical devices is provided wherein the device is impregnated with processed collagen, the protein of the processed collagen is fixed by a cross-linking agent, and the device as impregnated is treated with an anticoagulant and with a plasticizing agent.

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