Antithrombotic agents

Details Antithrombotic agents Antithrombotic agents

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) A61K 31/40 (2006.01) A61K 31/435 (2006.01) A61K 38/05 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 211/60 (2006.01) C07D 401/06 (2006.01) C07K 5/02 (2006.01) C07K 5/062 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) C07K 5/097 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2183464

This invention relates to thrombin inhibiting compounds having the formula (I): X-Y-NH-(CH2)r-G where X, Y, r and G have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors, and thromboembolic disorder agents.

L'invention concerne des composés inhibant la thrombine et correspondant à la formule (I): X-Y-NH-(CH¿2?)¿r?-G, où X, Y, r et G présentent les valeurs définies dans la description. Elle concerne aussi des formulations pharmaceutiques contenant ces composés, et leurs procédés d'utilisation en tant qu'inhibiteurs de la thrombine, inhibiteurs de coagulation et agents de traitement des troubles thromboemboliques.

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