Antithrombotic agents

Details Antithrombotic agents Antithrombotic agents

C - Chemistry, Metallurgy

07

K

C07K 5/097 (2006.01) A61K 31/395 (2006.01) A61K 38/06 (2006.01) C07D 207/16 (2006.01) C07D 209/42 (2006.01) C07D 209/52 (2006.01) C07D 401/00 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07K 5/02 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2180141

This invention relates to L-arginine aldehyde derivatives, having formula (I) where X and Y have the values defined in the description, as well as phar- maceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors, and thromboembolic disorder agents.

L'invention concerne des dérivés d'aldéhydes de L-arginine de formule (I) où X et Y ont les valeurs définies dans la description. Elle concerne aussi des formulations pharmaceutiques contenant ces composés, et des procédés ayant trait à leur utilisation comme inhibiteurs de thrombine ou de coagulation et d'agents de traitement des troubles thromboemboliques.

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