C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 31/395 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07D 205/04 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07K 5/065 (2006.01) C07K 5/078 (2006.01) C07K 5/08 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2184188
This invention relates to L-arginine aldehyde derivatives having formula (I) where R1, X and Y have the values defined in the description, as well as pharmaceutical formulations containing those compounds and methods of their use as thrombin inhibitors, coagulation inhibitors and thromboembolic disorder agents.
L'invention concerne des dérivés d'aldéhyde de L-arginine représentés par la formule (I), dans laquelle R?1¿, X et Y ont les valeurs définies dans la description, des formulations contenant ces composés, ainsi que leur procédés d'utilisation en tant qu'inhibiteurs de la thrombine, inhibiteurs de coagulation et agents antithromboemboliques.
Schacht Aaron Leigh
Shuman Robert Theodore
Smith Gerald Floyd
Wikel James Howard
Wiley Michael Robert
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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