A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/208, 167/234
A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 275/04 (2006.01)
Patent
CA 1120859
ABSTRACT ANTITHROMBOTIC COMPOSITIONS CONTAINING BENZISOTHIAZOLONES This invention relates to a pharmaceutical comp- position useful in the treatment of arterial thrombosis. A combination of a non-steroidal anti-inflammatory agent with a benzisothiazolone of formula (I) is found to be capable of inhibiting the aggregation of blood platelets to a greater degree than each of the components sep- arately. Image (I) R1 and R2 represent a variety of substituent groups; X represents a bond or an alkylene chain; and R rep- resents a heterocyclic group. When the anti-inflammatory agent contains a carb- oxylic acid group, the combination with compound (I) may be in the form of a salt.
312873
Baggaley Keith H.
Nunn Barbara
Baggaley Keith H.
Borden Ladner Gervais Llp
Nunn Barbara
LandOfFree
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