Antithrombotic imidazole derivatives

Details Antithrombotic imidazole derivatives Antithrombotic imidazole derivatives

C - Chemistry, Metallurgy

07

D

260/305, 260/314

C07D 233/64 (2006.01) C07D 233/54 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1197848

ABSTRACT This invention is concerned with certain triphenylimidazoles compounds of formula (I) Image (I) in which R and R' are identical or different and may be hydrogen;a lower alkyl having 1 to 4 carbons; phenyl; phenyl substituted with one or more lower alkyl groups having from 1 to 4 carbons, lower alkoxy groups having from 1 to 4 carbons or halogen atoms, e.g. Br or Cl; phenylalkyl (optionally substituted on the phenyl ring with one or more lower alkyl groups having from 1 to 4 carbons, lower alkoxy groups having 1 to 4 carbons or halogen atoms, e.g. Br or Cl); or taken together from a cyclic substituent of 5 or 6 members containing in addition to the nitrogen atom an optional second hetero atom selected from the groups consisting of oxygen, nitrogen and sulfur. This invention is also taken to include the acid addition salts and solvates of the compounds of formula (I). These compounds are useful as antithrombotic, antiinflammatory, antipyretic and analgesic agents.

396069

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