Antithrombotic polypeptides as antagonists of the binding of...

Details Antithrombotic polypeptides as antagonists of the binding of... Antithrombotic polypeptides as antagonists of the binding of...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/37 (2006.01) C07K 14/755 (2006.01) C07K 14/765 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2126092

2126092 9315200 PCTABS00163 La présente invention concerne des polypeptides recombinants composés d'un partie adhésive dérivée de la structure du vWF capable d'antagoniser au moins partiellement la liaison du vWF aux plaquettes et/ou au sous-endothélium, et d'une partie permettant sa stabilisation et sa présentation in vivo, leur préparation et des compositions pharmaceutiques les contenant.

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