A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
260/304, 195/89
A61K 31/42 (2006.01) C07D 311/00 (2006.01) C07D 313/00 (2006.01) C07D 493/22 (2006.01)
Patent
CA 1311434
ABSTRACT OF THE DISCLOSURE The present invention provides Rhizoxin in pure iso- lated form having the following characteristics: External appearance White powder Molecular formula: C35H47NO9 Molecular weight: 625 Melting point: 131-135°C Specific rotation: [.alpha.]24 + 201° (c=0.8, MeOH) D Ultraviolet absorption spectrum: Shown in Fig. 1. Infrared absorption spectrum: Shown in Fig. 2, in which chloroform is used as the solvent. Nuclear magnetic resonance spectrum: 1H and 13C nuclear magnetic resonance spectra are shown in Fig. 3. Mass spectrum: Shown in Fig. 4. Solubility in solvents: Easily soluble in benzene, chloroform, acetone, alco- hol, etc.; sparingly sol- uble in water, n-hexane. Elementary analysis: C H N Found (%) 66.94 7.78 2.04 Calculated (%) 67.18 7.57 2.23 useful for palliative relief and temporary remission of tumor on human beings and other mammals.
562417
Furukawa Jun
Iwasaki Shigeo
Kobayashi Hisayoshi
Matsuda Izumi
Noda Takahito
Marks & Clerk
National Institute For Agro-Environmental Sciences
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