Antitumor agent comprising 6'-amidino-2'-naphthyl4-...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31/245 (2006.01) A61K 45/00 (2006.01) A61P 1/18 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2616534

Disclosed is a novel anti-tumor agent which does not induce any serious adverse side effect or drug resistance which is a disadvantage of conventional anti-tumor agents and shows a high therapeutic index. Particularly disclosed is a novel therapeutic agent or therapeutic method which is effective on pancreatic cancer on which there is found no effective therapeutic method or chemotherapeutic agent at the present time and can prevent cancerous metastasis and invasion. An anti-cancer agent, particularly a therapeutic agent for pancreatic cancer or cancer metastasis preventive agent, comprising 6'-amidino-2'-naphthyl4-guanidinobenzoate or a salt thereof, particularly nafamostat mesilate (also known under the general names "Futhan", "FUT" and "FUT175") which is a mesilate thereof as an active ingredient; and use of the anti-tumor agent such as FUT in combination with a conventional anti-cancer or anti-tumor agent, particularly preferably gemcitabine hydrochloride.

La présente invention concerne un nouvel agent antitumoral qui n'induit pas d'effet indésirable grave ou de résistance aux médicaments, contrairement aux agents antitumoraux classiques, et qui présente un indice thérapeutique élevé. Cette invention concerne en particulier un nouvel agent thérapeutique ou une nouvelle méthode thérapeutique qui est efficace sur le cancer du pancréas pour lequel aucune méthode thérapeutique ou agent chimiothérapeutique efficace n'existe à ce jour et qui peut prévenir la métastase et l'invasion du cancer. Un agent anticancéreux, en particulier un agent thérapeutique pour le cancer du pancréas ou un agent de prévention des métastases du cancer, comprenant du 6'-amidino-2'-naphthyl4-guanidinobenzoate ou un sel de celui-ci, en particulier du mésilate de nafamostat (aussi connu sous les noms généraux de "Futhan", "FUT" et "FUT175"), qui est un mésilate de celui-ci, comme ingrédient actif. Cette invention concerne également l'utilisation de l'agent antitumoral tel que FUT en combinaison avec un agent anticancéreux ou antitumoral conventionnel, en particulier de préférence le chlorhydrate de gemcitabine.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Antitumor agent comprising 6'-amidino-2'-naphthyl4-... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Antitumor agent comprising 6'-amidino-2'-naphthyl4-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Antitumor agent comprising 6'-amidino-2'-naphthyl4-... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1983452

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.