Antitumor agents

Details Antitumor agents Antitumor agents

C - Chemistry, Metallurgy

07

D

C07D 207/16 (2006.01) A61K 31/122 (2006.01) A61K 31/16 (2006.01) A61K 31/198 (2006.01) A61K 31/22 (2006.01) A61K 31/401 (2006.01) A61K 38/06 (2006.01) C07C 49/737 (2006.01) C07C 69/013 (2006.01) C07C 323/58 (2006.01) C07C 323/59 (2006.01) C07C 323/60 (2006.01) C07K 5/037 (2006.01) C07K 5/062 (2006.01) C07K 5/083 (2006.01) C07K 5/103 (2006.01)

Patent

CA 2321149

The present invention provides compounds of general formula (I) or (II): wherein R1, R2, R3, R4, R5, R6, and R7 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising compounds of formula (I) or (II), intermediates and processes useful for preparing compounds of formula (I) or (II), and methods comprising inhibiting tumor growth or treating cancer by administering one or more compounds of formula (I) or (II).

L'invention concerne des composés représentés par la formule générale (I) ou (II), dans laquelle, R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6? et R?7¿ ont l'une des valeurs spécifiée dans la description, des sels pharmaceutiquement acceptables de ces composés ainsi que des compositions pharmaceutiques comprenant des composés représentés par la formule (I) ou (II), des intermédiaires, des procédés de préparation de ces composés, et des procédés consistant à inhiber la croissance tumorale ou à traiter le cancer par administration d'un ou plusieurs de ces composés.

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