Antitumor agents

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/05 (2006.01) A61K 31/34 (2006.01) A61K 31/343 (2006.01) A61K 31/352 (2006.01)

Patent

CA 2296478

Antitumor agents containing as the active ingredient a compound selected from among pallidol, miyabenol A, miyabenol C, .alpha.-viniferin, kobophenol A, 4,4- (1,3-butadiene-1,4-diyl)bisphenol, leachianol A, leachianol B, leachianol F, leachianol G, hopeaphenol and davidiol A and salts thereof. Because of having excellent topoisomerase II inhibitory effects, these compounds are usable as antitumor agents.

La présente invention concerne des agents antinéoplastiques dont le principe actif est un composé de différentes molécules ou de certains de leurs sels. Ces molécules sont les pallidol, miyabénol A, miyabénol C, .alpha.-viniférine, cobophénol A, 4,4-(1,3-butadiène-1,4-diyl)bisphénol, léachianol A, léachianol B, léachianol F, léachianol G, hopéaphénol et davidiol A. De par leur action inhibitrice vis-à-vis de la topoisomérase II, ces composés sont des agents antinéoplastiques tout désignés.

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